AB SCIEX 4000 QTrap UPLC/MS/MS coupled with Shimadzu 30A UPLC Nexera LC System
Key Features
- Robust hybrid triple quadruple/linear ion trap mass spectrometer
- High-pressure tolerance
- Fast, better separation
Application
- Study physical, chemical, or biological properties of a variety of compounds
- Drug discovery and development
- Metabolite identification and quantitation
- Proteomic applications (post-translationally modified protein discovery/protein identification)
- Biomarker validation (mass range, 5-2800 m/z.)
AB SCIEX QTrap 6500 UPLC-MS/MS coupled with Shimadzu Nexera X2 UHPLC System
Key Features
- Scan rates of up to 20,000 Da/sec
- 20ms polarity switch
- Quantitative MRM3 workflows
- Linear ion trap capabilities
- Detection of analytes with rapid Data Dependent Acquisition (DDA)
- Data Independent Acquisition (DIA) strategy, SWATH technology
Application
- Include all capabilities of AB SCIEX 4000 qtrap UPLC/MS/MS system
- Achieve lowest limits of quantitation in complex matrices
- Obtain comprehensive peptide sequence confirmation and simplify MRM assay development of peptide quantification
- Simultaneously quantitate mrms and perform full library scans to search for contaminants
SCIEX X500B QTOF System
Key Features
- Robust, high-performance high-resolution MS/MS system
- High mass resolution (>30,000 resolution)
- High mass accuracy (<1ppm accuracy for m/z>50amu)
- Removal of interference from complex sample matrices
- Quantify linearly up to 4 orders of magnitude
- Identify analytes based on MS/MS (IDA and SWATH™ MS/MSALL, ion ratios and MS/MS spectra)
Application
- Identify metabolites
- Analyze larger molecule
Waters HPLC and UPLC systems
Key Features
- Three different Waters models coupled with a broad range of detectors – PDA, dual λ absorbance, UV/VIS, and fluorescence
- Enhanced separation resolution
- Increased sample through-put
Application
- Drug discovery
- Analyze drugs/metabolites in biological samples.
- In-vitro diagnostic test to analyze compounds (diagnostic indicators/ therapeutically monitored compounds)